At times we all seem to experience a pessimistic sense of inadequacy. Sometimes we just need to see things from a different perspective. Fes and Ernst are two parts of the same. While knowing they are a figment of the personalities of the webcomic artist, they know that they are, in turn, prisoners of a world of their own making. They make the best of things as a contrasting-buddy-team.
A shot from Strip #36, #16 of current Arc:

http://fesworks.xepher.net/home.php
Currently Updating MWF, with bonus random comics on Sundays.
The humor is a bit weird for most people, and tends to be on the inside and "WTF". But its been clearly working for me. Originally intended to a a random, pencil-sketch comic, it has developed into an inked and greyscaled comic with an Arc that is currently running with many plans for progression.
Next week (on 9-20 or 9-22) Lucy from Mat Sherer's Badly Drawn Kitties will be a special guest to the comic! (I have obtained his permission to use her from Mat
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EDIT: I should add:
The comic is rated Web 14
The world of which the comic exists is a half Human and half Anthro. Since the land animals are Anthromorphic, there needed to be a substitution for the wildlife and food sources. While trying to come up with the weiredest thing, I thouhg that "Bugs" would be the new wildlife... only bugs are bigger than normal (think: the grasshopper is the new "bunny"). And they need to be bigger because they are also the food source.
The fourth wall is broken occasionally when the two complain about the comic (or that the wildlife is large bugs), but its intentional, minimal, in character and in conversation (not facing the 4th wall). They mostly live with the other characters that have no clue.
Notable, Rememorable comics:
"Elbutt"
http://fesworks.xepher.net/00024a.htm
"Walking Stick or Beating Stick
http://fesworks.xepher.net/00028a.htm