Hmm, well I don't think it's a shout out, but Pride from Fullmetal Alchemist: Brotherhood has a monster form that's similar looking to Alucard's at least. He's more stabby than shooty, but he's certainly got that whole "tons of eyes and toothy mouths from the amorphous shadows" thing going on.
I wonder, does anybody know if that type of thing is an actual trope, or is this just a case of people having a similar idea about what's really, really freaky?
"I refuse to have a battle of wits against an unarmed opponent."
"Ah, but I am a master of unarmed combat!"