Fast and silly would be the Cup of Ka' etc. Just plain lettering a la 'Frankie Goes to Hollywood'. (Is there a proper
name for that style of block formatting?)
It'd be good for questions. Maybe the squidling on the opposite side?
BTW, although they're rarely formatted well -- by others, of course -- the CafePress messenger bags are REALLY nice. I'm using my Winged Trilobite bag for my current comics and graphic novels, but it deserves better use than that with all the pockets and such it has.
What about something with Alan's 'COOONNNNNN!!!' bellow? Great pun.
Good one-frame gag for formatting on stuff.