Well... I'm going to be honest here and say that in the begining of the strip I sort of got confused with the story. I didn't really understand what was happening.
Let see...A girl grew an extra -ahem- body part/organ and then something about she liked it but now she's dead. eh...then it jumped over to the butt boy and I could follow a little bit there. I don't understand why he has to insert fluids into these ladies -ahehem- yeahstuffness...but I'm guessing that'll come later on in the story line, eh, right?
Hey - I really liked where you were going with the rant. I'm guessing that was the head demon person and it's assistant. I thought it was clever that you decided to make the comic site importance as part of your comic. Just out of curiosity, is your comic site the "perfect product"? Cuz, if that's where your going with it then I think you are brilliant.
Sir you have a few plot holes in the beginning. But I don't suggest you go back and redo them - what's best to clear this up is to come back around and explain things later. Plug the holes in the later episodes.
Other things that bothered me slightly were the fact that the boobs of the chicks in some of the scenes were like chameleon eye balls - pointing in completely different directions. Remember that even when a girl with big knockers/or even little ones, moves around or jumps up and down - gravity does affect them big time. (Along with gravity, a females body shape affects the way the boobs rest on their torso. Womens breasts are pectoral muscles - so they aren't like bubbles attatched to the chest - they have muscles that link them to the deltoids and the obliques and other areas I'm sure. I've studied anatomy and figure drawing extensively.)
-Eheheh well I guess it doesn't really matter that much if you don't want to make the boobies semi-realistic. (Wow a whole paragraph on boobies!

)
Oh and the perspective of the girls(Epa, lala, stitches) on one of the pages was kind of wierd. But that probably wont matter if you're going for surreal or dreamlike or whatever.
As a whole, I think you're off to a good start. I've read alot...and I mean alot...of online comics. I've even read quite a few regular take-to-the-bathroom and-read regular and trade paperback comics.
I want to see more of this comic - so chop chop - feed me more, for I am hungry.