well i tell ya Josh, when you said you were resolving your decision today, what i saw on the front page was what i had hoped against. Even though i only discovered your comic earlier this week, as i told you, i thought it to be one of my greatest webcomic discoveries in ages.
I know exactly what it's like to be stuck in what seems a dead end position in life and how a lot seems meaningless because of it. I was like that last year and earlier this year. What did i do? i instigated change! I quit my job at the local supermarket deli, i quit my arts degree at the local university (which i was failing) and i flew half way across the world to Seattle where i've been studying animation for 6 months now and have been loving every second of it! I've also rediscovered a passion for drawing the old comic i quit earlier this year and that re-debuts today, the 2nd year anniversary of my comic site (yay!).
Anyway mate, if any advice at all, i'd say change is probably the best thing (which you said you're thinking about yourself). How drastic a change this may be, well that's of course totally up to you. All i can say is try and get some fresh air blown into what sounds like quite a deep rut you're stuck in.
In the meantime, i think i might send you a guest comic soon. ^^
Hope it all works out for ya.